Issue 6, 2002

Direct catalytic asymmetric aldol reactions of aldehydes

Abstract

The development of a direct catalytic enantioselective aldol reaction of aldehydes with activated carbonyl compounds catalyzed by chiral amines is presented and the potential demonstrated by the synthesis of optically active β-hydroxycarboxylic acid derivatives.

Graphical abstract: Direct catalytic asymmetric aldol reactions of aldehydes

Article information

Article type
Communication
Submitted
22 Jan 2002
Accepted
08 Feb 2002
First published
22 Feb 2002

Chem. Commun., 2002, 620-621

Direct catalytic asymmetric aldol reactions of aldehydes

A. Bøgevig, N. Kumaragurubaran and K. Anker Jørgensen, Chem. Commun., 2002, 620 DOI: 10.1039/B200681B

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