Issue 8, 2002
From the journal:

Chemical Communications

A modified molecular beacon combining the properties of TaqMan probe

De-Ming Kong,a   Long Gu,a   Han-Xi Shen*a  and  Huai-Feng Miab  

* Corresponding authors

a The State Key Lab of Functional Polymer Materials for Adsorption and Separation, Chemical School, Nankai University, Tianjin, China
E-mail: hxshen@eyou.com
Tel: +86-22-23505324

b Medical School, Nankai University, Tianjin, China

Abstract

A modified molecular beacon that possesses a stem-hairpin structure as seen in conventional molecular beacons and can be cleaved during PCR is designed, and it can specifically recognize the presence of the target and was obviously more sensitive than conventional molecular beacons.

Graphical abstract: A modified molecular beacon combining the properties of TaqMan probe

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Article information

DOI
https://doi.org/10.1039/B200592A
Article type
Communication
Submitted
18 Jan 2002
Accepted
07 Mar 2002
First published
20 Mar 2002

Chem. Commun., 2002, 854-855

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A modified molecular beacon combining the properties of TaqMan probe

D. Kong, L. Gu, H. Shen and H. Mi, Chem. Commun., 2002, 854 DOI: 10.1039/B200592A

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