Issue 9, 2002
From the journal:

Chemical Communications

A highly enantioselective synthesis of cyclic α-amino acids involving a one-pot, single catalyst, tandem hydrogenation–hydroformylation sequence†

Euneace Teoh,a   Eva M. Campi,a   W. Roy Jacksona  and  Andrea J. Robinson*a  

* Corresponding authors

a Centre for Green Chemistry and School of Chemistry, PO Box 23, Monash University, Victoria, Australia
E-mail: A.Robinson@sci.monash.edu.au
Fax: 61 03 9905 4597
Tel: 61 03 9905 4553

Abstract

Tandem enantioselective hydrogenation followed by a hydroformylation–cyclisation sequence leading to cyclic α-amino acids with ee’s >95% can be achieved in a single pot, one catalyst system by successive reactions of prochiral dienamide esters with H2 followed by H2/CO using Rh(I)-DuPHOS.

Graphical abstract: A highly enantioselective synthesis of cyclic α-amino acids involving a one-pot, single catalyst, tandem hydrogenation–hydroformylation sequence

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B200374K
Article type
Communication
Submitted
10 Jan 2002
Accepted
12 Mar 2002
First published
04 Apr 2002

Chem. Commun., 2002, 978-979

Permissions

Request permissions

A highly enantioselective synthesis of cyclic α-amino acids involving a one-pot, single catalyst, tandem hydrogenation–hydroformylation sequence

E. Teoh, E. M. Campi, W. R. Jackson and A. J. Robinson, Chem. Commun., 2002, 978 DOI: 10.1039/B200374K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements