Issue 3, 2002
From the journal:

Chemical Communications

In vivo cleavage of a target RNA by copper kanamycin A. Direct observation by a fluorescence assay†

Chun-An Chena  and  J. A. Cowan*a  

* Corresponding authors

a Evans Laboratory of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio, USA
E-mail: cowan@chemistry.ohio-state.edu

Abstract

A novel fluorescence assay to monitor in vivo cleavage chemistry of RNA target sequences has been established and used to demonstrate the activity of copper aminoglycoside mediated degradation of RNA in bacterial cells.

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Article information

DOI
https://doi.org/10.1039/B108439A
Article type
Communication
Submitted
17 Sep 2001
Accepted
06 Nov 2001
First published
17 Jan 2002

Chem. Commun., 2002, 196-197

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In vivo cleavage of a target RNA by copper kanamycin A. Direct observation by a fluorescence assay

C. Chen and J. A. Cowan, Chem. Commun., 2002, 196 DOI: 10.1039/B108439A

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