Chiral discrimination for enantiomers of amino acids using an electrochemiluminescence method

Abstract

On the basis of our new findings that the enantiomers of some amino acids can interact with Ru(bpy)₃²⁺ by electron-transferring to induce different luminescence spectra, depending on their electrochemical enantioselectivities to Ru(bpy)₃²⁺, an electrochemiluminescence (ECL) chiral discrimination method has been developed. The L and D enantiomers of amino acids in synthetic samples have been determined based on the luminous intensities; the relative errors were less than or equal to 6.0%. The enantioselectivity of the enantiomers to Ru(bpy)₃²⁺ was demonstrated by chronocoulometry.