Issue 21, 2001

Polyhalogenated heterocyclic compounds. Part 47.1 Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

Abstract

A sequence of nucleophilic aromatic substitution and palladium catalysed coupling processes were used to transform pentafluoropyridine into various pyridine derivatives that bear five different functional groups.

Graphical abstract: Polyhalogenated heterocyclic compounds. Part 47.1 Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

Supplementary files

Article information

Article type
Paper
Submitted
04 Jul 2001
Accepted
12 Sep 2001
First published
09 Oct 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 2788-2795

Polyhalogenated heterocyclic compounds. Part 47. Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

R. D. Chambers, P. R. Hoskin, G. Sandford, D. S. Yufit and J. A. K. Howard, J. Chem. Soc., Perkin Trans. 1, 2001, 2788 DOI: 10.1039/B105950P

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