Issue 4, 2001

One-pot condensation of 2-arylpropenes with formaldehyde and ammonium chloride: the synthesis of aryl substituted pyridines and 5,7,11-trioxa-1-azatricyclo[7.3.1.03,8]tridecanes

Abstract

A mixture consisting of 2-arylpropene 1 or 2, formaldehyde and ammonium chloride condenses in a one-pot manner to yield 5,7,11-trioxa-1-azatricyclo [7.3.1.03,8]tridecanes 3 or 4. In the presence of manganese dioxide the reaction leads to 4-arylpyridines 5 or 6.

Article information

Article type
Paper

Mendeleev Commun., 2001,11, 154-155

One-pot condensation of 2-arylpropenes with formaldehyde and ammonium chloride: the synthesis of aryl substituted pyridines and 5,7,11-trioxa-1-azatricyclo[7.3.1.03,8]tridecanes

A. T. Soldatenkov, K. B. Polyanskii, A. W. Temesgen, S. A. Soldatova, N. D. Sergeeva, N. M. Kolyadina and N. N. Lobanov, Mendeleev Commun., 2001, 11, 154 DOI: 10.1070/MC2001v011n04ABEH001457

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