Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 2, 2001
Previous Article Next Article

An organic self-regulating microfluidic system

Author affiliations


In this paper we present an organic feedback scheme that merges microfluidics and responsive materials to address several limitations of current microfluidic systems. By using in situ fabrication and by taking advantage of microscale phenomena (e.g., laminar flow, short diffusion times), we have demonstrated feedback control of the output pH in a completely organic system. The system autonomously regulates an output stream at pH 7 under a range of input flow conditions. A single responsive hydrogel component performs the functionality of traditional feedback system components. Vertically stacked laminar flow is used to improve the time response of the hydrogel actuator. A star shaped orifice is utilized to improve the flow characteristics of the membrane/orifice valve. By changing the chemistry of the hydrogel component, the system can be altered to regulate flow based on hydrogels sensitive to temperature, light, biological/molecular, and others.

Back to tab navigation

Publication details

The article was received on 06 Sep 2001, accepted on 30 Oct 2001 and first published on 22 Nov 2001

Article type: Communication
DOI: 10.1039/B108078D
Citation: Lab Chip, 2001,1, 96-99

  •   Request permissions

    An organic self-regulating microfluidic system

    D. T. Eddington, R. H. Liu, J. S. Moore and D. J. Beebe, Lab Chip, 2001, 1, 96
    DOI: 10.1039/B108078D

Search articles by author