Layered double hydroxide fluoride: a novel solid base catalyst for C–C bond formation

Abstract

LDH-F hydrotalcite catalysts are found to be an efficient, environmentally attractive and selective solid base catalysts for 1,4-Michael addition and also for simple synthesis of α,β-unsaturated esters and nitriles by Knoevenagel condensation. The catalyst displayed unprecedented catalytic activity both in Knoevenagel and Michael reactions under mild liquid phase conditions at a greater rate compared with known solid bases and fluoride catalysts. The present ecofriendly catalyst is a potential alternative to soluble bases.