Issue 3, 2001
From the journal:

Green Chemistry

Microwave-accelerated Suzuki cross-coupling reaction in polyethylene glycol (PEG)

Vasudevan V. Namboodiri†a  and  Rajender S. Varma*a  

* Corresponding authors

a Clean Processes Branch, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, MS 443, 26 W. Martin Luther King Drive, Cincinnati, OH, USA.
E-mail: Varma.Rajender@epa.gov

Abstract

Polyethylene glycol (PEG) is found to be an inexpensive and non-toxic reaction medium for the microwave-assisted Suzuki cross-coupling of arylboronic acids with aryl halides. This environmentally friendly microwave protocol offers ease of operation and enables recyclability of catalyst and synthesis of a variety of substituted biaryls employing palladium chloride as catalyst and potassium fluoride as the base.

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Article information

DOI
https://doi.org/10.1039/B102337N
Article type
Paper
Submitted
13 Mar 2001
First published
29 May 2001

Green Chem., 2001,3, 146-148

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Microwave-accelerated Suzuki cross-coupling reaction in polyethylene glycol (PEG)

V. V. Namboodiri and R. S. Varma, Green Chem., 2001, 3, 146 DOI: 10.1039/B102337N

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