Efficient synthesis of the antigenic phosphoglycans of the Leishmania parasiteElectronic supplementary information (ESI) available: selected data for compounds 7, 8, 10 and 11. See http://www.rsc.org/suppdata/cc/b1/b106634j/
Abstract
Antigenic phosphoglycan repeats of the Leishmania parasite can be assembled in a flexible and efficient manner without involving any glycosidation steps, and the chain can be extended either towards the non-reducing (6′-OH) or reducing (1-OH) end suitable for synthesis of lipophosphoglycan, proteophosphoglycan and analogues.