Highly diastereoselective dihydride formation by activation of methanol with IrCl{(S)-binap}(PPh3)

Abstract

Reaction of [IrCl{(S)-binap}(PPh₃)] {(S)-3} with methanol gave one of the diastereomers of the cis,mer-dihydride, cis,mer-OC-6-44-A-[IrCl(H₂){(S)-binap}(PPh₃)] {(S)-4a} stereoselectively, the structure of which was determined crystallographically, whereas the reaction of (S)-3 with H₂ produced a 1∶1 mixture of the diastereomers of the cis,mer-dihydride, (S)-4a and cis,mer-OC-6-44-C-[IrCl(H₂){(S)-binap}(PPh₃)] {(S)-4b}.