Baker’s yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol, (+)-xanthorrhizol, (−)-curcuquinone and (+)-curcuhydroquinone
Abstract
Fermenting baker’s yeast converts the unsaturated )-(+) isomers. Enantiopure 6a–c are versatile chiral building blocks for the synthesis of
)-(+)-curcuphenol, (S
)-(+)-xanthorrhizol, (S
)-(−)-curcuquinone and (S
)-(+)-curcuhydroquinone.