Cycloaddition-mediated strategies for synthesis of perhydrobenzo[14,15]-14β-19-norsteroids
Abstract
Methods are described for sequential cycloaddition–fragmentation–recombination and ),17-dione 4. Similarly, it is shown that various 16α-alkenyl-14α,17α-ethenoestradiols undergo ready [3,3]-sigmatropic rearrangement to give functional variants of this pentacyclic system. Synthetic routes to novel (perhydrobenzo)[14,15]-14β-analogues of