Issue 24, 2000

A simple preparation of syn-NH-amide aldols and amide-Baylis–Hillman adducts via a Michael–aldol tandem process

Abstract

The thiolate- or selenolate-induced Michael–aldol tandem process using secondary α,β-unsaturated amides gave α-phenylthio- or α-phenylseleno-methyl-β-hydroxy amides syn-selectively, which were readily converted into NH-amide aldols or Baylis–Hillman adducts.

Supplementary files

Article information

Article type
Paper
Submitted
13 Jun 2000
Accepted
14 Sep 2000
First published
30 Nov 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 4499-4504

A simple preparation of syn-NH-amide aldols and amide-Baylis–Hillman adducts via a Michael–aldol tandem process

A. Kamimura, Y. Omata, H. Mitsudera and A. Kakehi, J. Chem. Soc., Perkin Trans. 1, 2000, 4499 DOI: 10.1039/B004721J

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