Issue 11, 2000

1,7-Asymmetric induction of chirality in a Mukaiyama aldol reaction using π-allyltricarbonyliron lactone complexes: highly diastereoselective synthesis of α-substituted β-hydroxy carbonyl compounds

Abstract

Silyl enol ethers derived from ethyl ketone functionalised π-allyltricarbonyliron lactone complexes undergo highly diastereoselective Mukaiyama aldol reactions with a variety of achiral aldehydes, with control of both α- and β-stereogenic centres.

Supplementary files

Article information

Article type
Paper
Submitted
14 Mar 2000
Accepted
24 Mar 2000
First published
09 May 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 1677-1683

1,7-Asymmetric induction of chirality in a Mukaiyama aldol reaction using π-allyltricarbonyliron lactone complexes: highly diastereoselective synthesis of α-substituted β-hydroxy carbonyl compounds

S. V. Ley and E. A. Wright, J. Chem. Soc., Perkin Trans. 1, 2000, 1677 DOI: 10.1039/B002056G

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