Synthesis of four possible stereoisomers of 1,2-epoxy-3-hydroxyerythrinans: total synthesis of an alkenoid-type erythrinan alkaloid, (±)-erythratidine1
Abstract
Four stereoisomers of 1,2-epoxy-3-hydroxyerythrinans are synthesized and their stereochemistries determined unambiguously. Of these, the 1,2α-epoxy-3α-alcohol 4 is converted to the alkenoid-type