Issue 10, 2000

The synthesis of vicinal halohydrin phosphates via highly regioselective ring opening of epoxides with dialkyl halophosphate

Abstract

Various titanium(IV) reagents catalyze the ring opening of epoxides by dialkyl halophosphates (added or formed in situ) under mild conditions to give the corresponding vicinal halohydrin phosphates in good yields with high regioselectivity.

Article information

Article type
Paper
Submitted
06 Dec 1999
Accepted
01 Mar 2000
First published
19 Apr 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 1651-1655

The synthesis of vicinal halohydrin phosphates via highly regioselective ring opening of epoxides with dialkyl halophosphate

Y. Ding and J. Hu, J. Chem. Soc., Perkin Trans. 1, 2000, 1651 DOI: 10.1039/A909613B

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