N-(2-Iodoethyl) and N-(3-iodopropyl)pyrimidines and purines undergo stereoselective conjugate radical addition with an optically active oxazolidinone acceptor to give syn-adducts that can be converted into pyrimidine and purine amino acids.
Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleic acid bases in their side chains
R. C. F. Jones, D. J. C. Berthelot and J. N. Iley, Chem. Commun., 2000, 2131 DOI: 10.1039/B006843H
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