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Issue 23, 2000
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Development of small peptides recognizing a monosaccharide by combinatorial chemistry

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Abstract

Small peptides selected from a library of 62000 chemically synthesized peptides were able to recognize a monosaccharide specifically and efficiently using both sandwiching and hydrogen bonding interactions, much like sugar-binding proteins (lectins) with the appropriate orientation of amino acid side chains.

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Article information


Submitted
18 Aug 2000
Accepted
09 Oct 2000
First published
07 Nov 2000

Chem. Commun., 2000, 2295-2296
Article type
Communication

Development of small peptides recognizing a monosaccharide by combinatorial chemistry

N. Sugimoto, D. Miyoshi and J. Zou, Chem. Commun., 2000, 2295
DOI: 10.1039/B006714H

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