Amavadine as a catalyst for the peroxidative halogenation, hydroxylation and oxygenation of alkanes and benzene

Abstract

Synthetic amavadine models, [V(HIDPA)₂]²⁻ and [V(HIDA)₂]²⁻ [where HIDPA and HIDA stand for the basic forms of 2,2′-(hydroxyimino)dipropionic and 2,2′-(hydroxyimino)diacetic acid, respectively], exhibit haloperoxidase- or peroxidase-type activities, and act as catalysts for the selective peroxidative monohalogenation, hydroxylation or oxo-functionalization of alkanes or aromatic compounds such as benzene and mesitylene at room temperature.