Issue 23, 2000
From the journal:

Chemical Communications

Enhancement of

Hossein Shabanya  and  George W. Gokel*a  

* Corresponding authors

a Bioorganic Chemistry Program and Dept. of Molecular Biology & Pharmacology, Washington University School of Medicine, 660 South Euclid Ave., Campus Box 8103, St. Louis, MO, USA.
E-mail: ggokel@molecool.wustl.edu

Abstract

A novel, pentamacrocyclic host molecule has been prepared in which four symmetry-equivalent diazacrown ethers lead to a dramatic enhancement in Na+ transport, across a phospholipid bilayer, relative to open-chained analogs lacking the fourth crown.

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Article information

DOI
https://doi.org/10.1039/B005436O
Article type
Communication
Submitted
28 Jun 2000
Accepted
16 Oct 2000
First published
20 Nov 2000

Chem. Commun., 2000, 2373-2374

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Enhancement of cation transport in synthetic hydraphile channels having covalently-linked headgroups

H. Shabany and G. W. Gokel, Chem. Commun., 2000, 2373 DOI: 10.1039/B005436O

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