Issue 12, 2000
From the journal:

Chemical Communications

Development of new methodology for the synthesis of functionalized α-fluorophosphonates and its practical application to the preparation of phosphopeptide mimetics

Akira Otaka,*a   Etsuko Mitsuyama,a   Hideaki Watanabe,a   Hirokazu Tamamuraa  and  Nobutaka Fujiia  

* Corresponding authors

a Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.
E-mail: aotaka@pharm.kyoto-u.ac.jp

Abstract

New methodology for the synthesis of functionalized α-fluorophosphonates which utilizes organocopper-mediated reduction has been developed and applied to the preparation of a monofluoromethyl-substituted phosphoserine mimetic-containing peptide.

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Article information

DOI
https://doi.org/10.1039/B002188L
Article type
Communication
Submitted
20 Mar 2000
Accepted
10 May 2000
First published
31 May 2000

Chem. Commun., 2000, 1081-1082

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Development of new methodology for the synthesis of functionalized α-fluorophosphonates and its practical application to the preparation of phosphopeptide mimetics

A. Otaka, E. Mitsuyama, H. Watanabe, H. Tamamura and N. Fujii, Chem. Commun., 2000, 1081 DOI: 10.1039/B002188L

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