Issue 9, 2000
From the journal:

Chemical Communications

Synthesis of carbonyl-bridged peptides containing an α-fluoroglycine residuePart 4 of series: Synthetic studies for novel structure of α-nitrogenousyl functionalized α-fluorocarboxylic acids.

Yoshio Takeuchi,*a   Kiyotoshi Kirihara,a   Kenneth L. Kirkb  and  Norio Shibataa  

* Corresponding authors

a Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama, 930-0194, Japan.
E-mail: takeuchi@ms.toyama-ac.jp

b Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA

Abstract

Gabriel reaction of hydantoins with bromofluoroacetate provides a general method for the synthesis of carbonyl-bridged peptides containing an α-fluoroglycine residue.

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Article information

DOI
https://doi.org/10.1039/B001265N
Article type
Communication
Submitted
15 Feb 2000
Accepted
29 Mar 2000
First published
18 Apr 2000

Chem. Commun., 2000, 785-786

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Synthesis of carbonyl-bridged peptides containing an α-fluoroglycine residue

Y. Takeuchi, K. Kirihara, K. L. Kirk and N. Shibata, Chem. Commun., 2000, 785 DOI: 10.1039/B001265N

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