Issue 22, 1999

Conformational equilibria in amino steroids derived from fusidic acid

Abstract

The conformation of ring A of the 3α-hydroxy-2β-piperidino steroid 9, derived from fusidic acid, has been investigated by 1H NMR and is determined by the polarity of the medium: it is primarily in a twist-boat conformation in a non-polar solvent and a chair conformation in a polar solvent.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1999, 3311-3314

Conformational equilibria in amino steroids derived from fusidic acid

W. S. Murphy and B. Sarsam, J. Chem. Soc., Perkin Trans. 1, 1999, 3311 DOI: 10.1039/A906998D

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