Issue 22, 1999

Stereoselective synthesis of 1′β-2′,3′-dideoxy-2′-bis(ethoxycarbonyl)methyluridine nucleosides by ring opening of cyclopropanated glycals

Abstract

Cyclopropanations of glycals followed by Lewis acid-mediated glycosylations with 5-substituted uracils afforded 1′β-2′,3′-dideoxy-2′-bis(ethoxycarbonyl)methyluridine nucleosides in a highly regiospecific and stereoselective manner in good yields.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1999, 3239-3241

Stereoselective synthesis of 1′β-2′,3′-dideoxy-2′-bis(ethoxycarbonyl)methyluridine nucleosides by ring opening of cyclopropanated glycals

J. Lim and Y. Hae Kim, J. Chem. Soc., Perkin Trans. 1, 1999, 3239 DOI: 10.1039/A906880E

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