Issue 8, 1999
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Synthesis of fluorinated phosphonoacetate derivatives of carbocyclic nucleoside monophosphonates and activity as inhibitors of HIV reverse transcriptase

Chris J. Hamilton  and  Stanley M. Roberts  

Abstract

The syntheses of compounds 8–10 are described; the compounds showed some activity as inhibitors of HIV reverse transcriptase (IC50 [gt-or-equal] 365 µM).

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Article information

DOI
https://doi.org/10.1039/A900339H
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1999, 1051-1056

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Synthesis of fluorinated phosphonoacetate derivatives of carbocyclic nucleoside monophosphonates and activity as inhibitors of HIV reverse transcriptase

C. J. Hamilton and S. M. Roberts, J. Chem. Soc., Perkin Trans. 1, 1999, 1051 DOI: 10.1039/A900339H

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