Synthesis of Phospholipids Bearing a Conjugated Oxo-polyunsaturated Fatty Acid Residue
Abstract
2-(15′-Oxo-5′,8′,11′,13′-eicosatetraenoyl)-1-stearoyl-sn-glycerol(3)phosphocholine (APC-CO) 1 and 2 and 2-(13′-oxo-9′,11′-octadecadienoyl)-1-stearoyl-sn-glycero(3)phosphocholine (LPC-CO) 3 are synthesized and an analytical system established for the determination of geometrical isomers at the 13′ position of APC-CO.