Issue 5, 1999

Tin-mediated Organic Reactions: a Practical Method for the Synthesis of β-Hydroxynitriles and β-Hydroxyketones

Abstract

In the presence of chlorotrimethylsilane, the tin mediated addition of bromoacetonitrile or α-bromacetophenone to aldehydes in THF gives β-hydroxynitriles or β-hydroxyketones in moderate to good yields.

Article information

Article type
Paper

J. Chem. Res. (S), 1999, 318-319

Tin-mediated Organic Reactions: a Practical Method for the Synthesis of β-Hydroxynitriles and β-Hydroxyketones

P. Sun and B. Shi, J. Chem. Res. (S), 1999, 318 DOI: 10.1039/A809418G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements