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Issue 20, 1999
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Glycosidase-catalysed synthesis of α-galactosyl epitopes important in xenotransplantation and toxin binding using the α-galactosidase from Penicillium multicolor

Abstract

The α-galactosidase from Penicillium multicolor catalyses highly regioselective galactosyl transfer on to mono- and di-saccharide acceptors that have a non-reducing terminal galactose unit to give products containing the α-D-Galp-(1→3)-D-Galp epitope found on pig tissue and which is responsible for the hyperacute rejection response in xenotransplantation of pig organs into man.

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Article type: Paper
DOI: 10.1039/A906020K
Citation: Chem. Commun., 1999,0, 2065-2066

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    Glycosidase-catalysed synthesis of α-galactosyl epitopes important in xenotransplantation and toxin binding using the α-galactosidase from Penicillium multicolor

    S. Singh, M. Scigelova and D. H. G. Crout, Chem. Commun., 1999, 0, 2065
    DOI: 10.1039/A906020K

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