Extremely selective Mg(ClO4)2 mediated removal of Bpoc/Ddz moieties suitable for the solid phase peptide synthesis of thioxo peptides
Abstract
Mg(ClO4)2 in organic solvents acts as an extremely mild reagent for repetitive Bpoc/Ddz deprotection during solid phase peptide synthesis even in the presence of the acid labile thioxo amide moiety with excellent yields.
 
                



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