Issue 17, 1999

New synthesis of a useful C3 chiral building block by a heterogeneous method: enantioselective hydrogenation of pyruvaldehyde dimethyl acetal over cinchona modified Pt/Al2O3 catalysts

Abstract

The first satisfactory application of the heterogeneous cinchona-modified Pt catalyst system for the synthesis of a C3 chiral building, namely, the highly enantioselective (up to 96.5% ee) hydrogenation of pyruvaldehyde dimethyl acetal to lactaldehyde dimethyl acetal is described.

Article information

Article type
Paper

Chem. Commun., 1999, 1725-1726

New synthesis of a useful C3 chiral building block by a heterogeneous method: enantioselective hydrogenation of pyruvaldehyde dimethyl acetal over cinchona modified Pt/Al2O3 catalysts

B. Török, K. Balázsik, M. Bartók, K. Felföldi and M. Bartók, Chem. Commun., 1999, 1725 DOI: 10.1039/A904694A

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