The first regio- and chemo-selective synthesis of fully substituted cyclooctatetraenes from two or three different alkynes was achieved using the cross-coupling between 1,4-dicuprabuta-1,3-dienes and 1,4-diiodobuta-1,3-dienes.
Y. Yamamoto, T. Ohno and K. Itoh, Chem. Commun., 1999, 1543 DOI: 10.1039/A904556B
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