A novel and simple method has been developed to obtain penem analogs with biologically interesting functionalities, which combines aromatic aldehydes with thioisomünchnones, a readily available class of mesoionic heterocycles.
M. Avalos, R. Babiano, P. Cintas, J. L. Jiménez, I. López, J. C. Palacios, M. B. Hursthouse and M. E. Light, Chem. Commun., 1999, 1589 DOI: 10.1039/A904333K
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