Issue 8, 1999

The facile synthesis of α-aryl-α-hydroxy esters via one-pot vicarious nucleophilic substitution and oxidation

Abstract

The anion produced by the vicarious nucleophilic substitution reaction of nitroarenes and α-chloro esters is hydroxylated by the action of air and benzaldehyde, thereby producing α-hydroxy esters.

Article information

Article type
Paper

Chem. Commun., 1999, 689-690

The facile synthesis of α-aryl-α-hydroxy esters via one-pot vicarious nucleophilic substitution and oxidation

N. J. Lawrence, O. Lamarche and N. Thurrab, Chem. Commun., 1999, 689 DOI: 10.1039/A900986H

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