Issue 5, 1999

The thiyl radical-mediated isomerization of cis-monounsaturated fatty acid residues in phospholipids: a novel path of membrane damage?

Abstract

Thiyl radicals, generated from biologically relevant thiols under biomimetic conditions, reversibly attack the double bonds of unsaturated phospholipids containing cis-fatty acid residues either in lipid solutions or lipid vesicles, thus producing phospholipids containing trans-fatty acid residues in high yield.

Article information

Article type
Paper

Chem. Commun., 1999, 407-408

The thiyl radical-mediated isomerization of cis-monounsaturated fatty acid residues in phospholipids: a novel path of membrane damage?

C. Ferreri, C. Costantino, C. Chatgilialoglu, C. Ferreri, L. Landi and Q. G. Mulazzani, Chem. Commun., 1999, 407 DOI: 10.1039/A809674K

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