Transformation of fusicocca-2,10(14)-dien-8β-ol into fusicoccin J by the fusicoccin-producing fungus, Phomopsis (Fusicoccum) amygdali. Support for the intermediacy of fusicocca-2,10(14)-diene in the fusicoccin biosynthesis

Abstract

(+)-Fusicocca-2,10(14)-diene, isolated recently by the authors, is most likely a genuine hydrocarbon intermediate in the biosynthesis of fusicoccin, as its 8β-hydroxy derivative is smoothly and efficiently converted into fusicoccin J by the fusicoccin-producing fungus, Phomopsis (Fusicoccum) amygdali F6.