The regio- and stereo-selective ring expansion of chiral N-(α-amino acyl)aziridine-2-imides to oxazolines and subsequent ring opening to optically pure threonine-containing dipeptides with the desired stereochemistry is described.
G. Cardillo, L. Gentilucci and A. Tolomelli, Chem. Commun., 1999, 167 DOI: 10.1039/A807063F
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