Catalytic antibodies: prospects for the use in organic synthesis

Abstract

Data on catalytic antibodies as a new generation of biocatalysts are reviewed. The principles used in the design, and the methods for the preparation of all presently known classes of catalytic antibodies, which catalyse particular conversions of organic compounds, are discussed. Data on the efficiency, regio- and stereospecificity and mechanisms of action of catalytic antibodies are presented and their possible applications in fine organic synthesis are considered. The bibliography includes 124 references