Easy access to various substituted 4-aminocyclopentenes by rearrangement of 2-ethenyl-substituted cyclopropylamines
Abstract
A variety of 2-ethenyl-substituted cyclopropylamines upon flash vacuum pyrolysis or under silver nitrate catalysis cleanly undergo ring enlargement and afford high yields (up to 95%) of 4-aminocyclopent-1-enes, some of which have unprecedented substitution patterns.