Issue 20, 1998

A novel and regioselective pyridine-ring formation by Lewis acid-induced cyclisation of 2-(N-allylbenzylamino)-3-[2,2-bis(ethoxycarbonyl)vinyl]pyrido[1,2-a]pyrimidin-4(4H)-one

Abstract

The Lewis acid-induced cyclisation of 2-(N++ -allylbenzylamino)-3-[2,2-bis(ethoxycarbonyl)vinyl]pyrido[1,2-++ a]pyrimidin-4(4H)-one 1a, which provides a novel and regioselective synthetic approach to the fused pyridine-ring, is described for the first time.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1998, 3327-3330

A novel and regioselective pyridine-ring formation by Lewis acid-induced cyclisation of 2-(N-allylbenzylamino)-3-[2,2-bis(ethoxycarbonyl)vinyl]pyrido[1,2-a]pyrimidin-4(4H)-one

M. Noguchi, H. Yamada and T. Sunagawa, J. Chem. Soc., Perkin Trans. 1, 1998, 3327 DOI: 10.1039/A805868G

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