Issue 20, 1998

Asymmetric synthesis of alkaloid (–)-(2S,4S ) SS 20846 A and its C-4 epimer

Abstract

A diastereoselective intramolecular Mannich reaction using planar chiral iron dienal complexes is employed to prepare optically pure 2,4-disubstituted piperidines. This methodology is applied to the synthesis of natural alkaloids (–)-6 and (–)-7.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1998, 3485-3492

Asymmetric synthesis of alkaloid (–)-(2S,4S ) SS 20846 A and its C-4 epimer

I. Ripoche, J. Canet, B. Aboab, J. Gelas and Y. Troin, J. Chem. Soc., Perkin Trans. 1, 1998, 3485 DOI: 10.1039/A804288H

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