Issue 15, 1998

Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine

Abstract

Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular ‘conjugate’ addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1998, 2255-2258

Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine

F. Heaney, S. Bourke, C. Burke, D. Cunningham and P. McArdle, J. Chem. Soc., Perkin Trans. 1, 1998, 2255 DOI: 10.1039/A802750A

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