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The hydroxylactones 4a–b (both available in optically pure form from biocatalytic processes) have been used in the preparation of carbovir, 1592U89, and their six-membered ring analogues.
H. F. Olivo and J. Yu, J. Chem. Soc., Perkin Trans. 1, 1998, 391 DOI: 10.1039/A708261D
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