New enantiomerically pure oligomeric macrocycles based on a 3,4-dihydroxypyrrolidine nucleus
Abstract
(3S,4S)-N-Benzyl-3,4-dihydroxypyrrolidine 1 has been used as a building block for new enantiopure macrocyclic polyesters. Two different synthetic approaches are presented leading to complementary results. The structure of the macrocycles synthesized has been confirmed by NMR spectroscopy and FAB mass spectrometry, and that for dimer 8 has been confirmed by X-ray analysis.