Issue 4, 1998

1,3,4-Oxa(thia)diazino [i,,j]-annelated quinolines: a new type of key intermediate in the synthesis of tricyclic fluoroquinolones

Abstract

The synthesis of new derivatives of 1,3,4-oxa(thia)diazino[6,5,4-i,,j]quinolines, which have a structure that is very similar to the ofloxacin skeleton, by intramolecular cyclizations of ethyl 3-(R-carbonylhydrazino)- and 3-(R-thiocarbonylhydrazino)-substituted 2-polyfluorobenzoyl acrylates, is described.

Article information

Article type
Paper

Mendeleev Commun., 1998,8, 131-133

1,3,4-Oxa(thia)diazino [i,,j]-annelated quinolines: a new type of key intermediate in the synthesis of tricyclic fluoroquinolones

G. N. Lipunova, E. V. Nosova, V. N. Charushin, L. P. Sidorova and O. M. Chasovskikh, Mendeleev Commun., 1998, 8, 131 DOI: 10.1070/MC1998v008n04ABEH000986

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