Issue 1, 1998

Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure

Abstract

Treatment of 1,2- (or 1,4)-dimethoxybenzene with isobutylene oxide and an appropriate nitrile RCN in concentrated sulfuric acid leads to 1-R-6,7-(or 5,8-)dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolines.

Article information

Article type
Paper

Mendeleev Commun., 1998,8, 17-18

Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure

V. A. Glushkov and Y. V. Shklyaev, Mendeleev Commun., 1998, 8, 17 DOI: 10.1070/MC1998v008n01ABEH000881

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