The 1,3-Dipolar Cycloaddition of 3-Methylene-N-substituted Isoindolones and Nitrones by Classical and Microwave Techniques: Reactivity and Stereochemical Studies
Abstract
The regiospecific 1,3-dipolar cycloaddition of various 3-methylene-N-substituted isoindolones 1 and nitrones 2 is depicted through a comparative study between classical heating and microwave irradiation; a survey of the relevant stereochemical features is made.