A Convenient Synthesis of 2-Aryl Derivatives of 4a,5,6,7,8,8a-Hexahydrospiro[4H-1,3-benzoxazine-4,1′-cyclohexane]
Abstract
Various 2-aryl derivatives of 4a,5,6,7,8,8a-hexahydrospiro[4H-1,3-benzoxazine-4,1′-cyclohexane] have been efficiently prepared by the acid-catalysed reaction of 2-(1-cyclohexen-1-yl)cyclohexanol with aromatic carbonitriles.