Preparation of α-Arylseleno-substituted Zinc and Copper Organometallics and their Application in the Synthesis of α-Arylselenomethyl Ketones

Abstract

α-Arylseleno-substituted zinc and copper organometallics, prepared by zinc insertion into the carbon–chlorine bond of α-chloromethyl aryl selenides and with CuCN–2LiCl transmetallation to the corresponding copper reagents, react with acyl chlorides to give α-arylselenomethyl ketones based on the formation of a new carbon–carbon bond.